Blood Gene Expression Reveal Pathway Differences Between Diet‐Sensitive and Resistant Obese Subjects Prior to Caloric Restriction

Abstract excerpt

Weight loss in response to caloric restriction displays significant interindividual heterogeneity. To develop early predictors of weight-loss success, we have compared whole-blood gene expression profiles of obese, diet-sensitive vs. obese, diet-resistant subjects prior to the initiation of clinically supervised caloric restriction. Pathway enrichment analysis of gene expression profiles by multiple applications...

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