Article
Association of the pentanucleotide repeat polymorphism in NOS2 promoter region with susceptibility to migraine in a Chinese population.
DNA and cell biology - 1 Feb 2011
Jia Shasha, Ni Jianqiang, Chen Shougong, Jiang Yuting, Dong Wanli, Gao Yuzhen
Abstract excerpt
Genes involved in the production of nitric oxide (NO) have been suggested as genetic factors for migraine. It has been studied whether polymorphisms in the genes encoding for different types of NO synthase (NOS) could be involved in the liability to migraine; however, most studies yield negative results. The pentanucleotide repeat microsatellite in the promoter region of inducible NOS (NOS2) shows highly...
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