Article
Phase II trial of gefitinib and everolimus in advanced non-small cell lung cancer.
Journal of thoracic oncology : official publication of the International Association for the Study of Lung Cancer - 1 Oct 2010
Price Katharine A, Azzoli Christopher G, Krug Lee M, Pietanza Maria C, Rizvi Naiyer A, Pao William, Kris Mark G, Riely Gregory J, Heelan Robert T, Arcila Maria E, Miller Vincent A
Abstract excerpt
INTRODUCTION: Concurrent signal transduction inhibition with the epidermal growth factor receptor (EGFR) inhibitor gefitinib and the mammalian target-of-rapamycin inhibitor everolimus has been hypothesized to result in enhanced antitumor activity in patients with non-small cell lung cancer (NSCLC). This phase II trial assessed the efficacy of the combination of gefitinib and everolimus in patients with advanced...
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