Rare genotype combination of the serotonin transporter gene associated with treatment response in severe personality disorder.

doi:10.1002/ajmg.b.31118

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Article

Rare genotype combination of the serotonin transporter gene associated with treatment response in severe personality disorder.

American journal of medical genetics. Part B, Neuropsychiatric genetics : the official publication of the International Society of Psychiatric Genetics - 5 Dec 2010

Perroud Nader, Salzmann Annick, Saiz Pilar A, Baca-Garcia Enrique, Sarchiapone Marco, Garcia-Portilla Maria P, Carli Vladimir, Vaquero-Lorenzo Concepción, Jaussent Isabelle, Mouthon Dominique, Vessaz Monique, Huguelet Philippe, Courtet Philippe, Malafosse Alain

Abstract excerpt

The insertion deletion (ins/del) polymorphism of the serotonin transporter gene (5-HTTLPR) has been associated with several psychiatric phenotypes and antidepressant's response. We investigated, in a large cohort of 5,608 controls and subjects suffering from various psychiatric disorders, the frequency of haplotypes and corresponding genotypes combining the 5-HTTLPR and the other serotonin transporter promoter...

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Identifiers

PMID: 20862697
DOI: 10.1002/ajmg.b.31118

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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