Article
Detecting selection in population trees: the Lewontin and Krakauer test extended.
Genetics - 1 Sept 2010
Bonhomme Maxime, Chevalet Claude, Servin Bertrand, Boitard Simon, Abdallah Jihad, Blott Sarah, Sancristobal Magali
Abstract excerpt
Detecting genetic signatures of selection is of great interest for many research issues. Common approaches to separate selective from neutral processes focus on the variance of F(ST) across loci, as does the original Lewontin and Krakauer (LK) test. Modern developments aim to minimize the false positive rate and to increase the power, by accounting for complex demographic structures. Another stimulating goal is...
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