Article
The frequency of factor V Leiden mutation, ACE gene polymorphism, serum ACE activity and response to ACE inhibitor and angiotensin II receptor antagonist drugs in Iranians type II diabetic patients with microalbuminuria.
Molecular biology reports - 1 Mar 2011
Rahimi Zohreh, Felehgari Vahid, Rahimi Mehrali, Mozafari Hadi, Yari Kheirollah, Vaisi-Raygani Asad, Rezaei Mansour, Malek-Khosravi Shohreh, Khazaie Habibolah
Abstract excerpt
The aim of present study was to determine if factor V Leiden (FVL) mutation and angiotensin converting enzyme insertion/deletion (ACE I/D) polymorphism are associated with diabetic nephropathy (DN) among Kurdish population from Western Iran. This case-control study comprised 144 unrelated adult type 2 diabetic mellitus patients (T2DM) including 72 patients with microalbuminuria and 72 age and sex matched patients...
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