Article
Application of genotype MTBDRplus in rapid detection of the Mycobacterium tuberculosis complex as well as its resistance to isoniazid and rifampin in a high volume laboratory in Southern China.
Molecular biology reports - 1 Mar 2011
Zhang Lei, Ye Yuanxing, Duo Lina, Wang Tingting, Song Xingbo, Lu Xiaojun, Ying Binwu, Wang Lanlan
Abstract excerpt
The alarmingly worsening epidemics of drug-resistant tuberculosis (TB) call urgent need for a simple method for the rapid detection of drug-resistant TB in clinical settings. In an attempt to establish a rapid procedure for laboratory diagnosis of TB and investigate the local TB epidemiology, molecular line probe assay of the Genotype MTBDRplus was used to identify Mycobacterium tuberculosis complex (MTBC) and...
Topics
- Antitubercular Agents
- Base Pairing
- China
- Clinical Laboratory Techniques
- DNA Probes
- Drug Resistance, Multiple, Bacterial
- Electrophoresis, Agar Gel
- Genes, Bacterial
- Genotype
- Humans