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Pseudomonas aeruginosaaccentuates epithelial-to-mesenchymal transition in the airway

16 Sept 2010

Abstract excerpt

Epithelial-to-mesenchymal transition (EMT) has been implicated in the dysregulated epithelial wound repair that contributes to obliterative bronchiolitis (OB) after lung transplantation. Acquisition of Pseudomonas aeruginosa in the transplanted airway has been shown to be a risk factor for the development of OB. We investigated the potential of P. aeruginosa to drive EMT in primary bronchial epithelial cells...

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PMID: 20847079
DOI: 10.1183/09031936.00088410

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