Article
Lack of p16 gene mutations in gastric cancers in Kashmir.
Asian Pacific journal of cancer prevention : APJCP - 1 Jan 2010
Bashir Sheikh Alina, Pandith Arshad Ahmad, Yousuf Adfar, Parveen Nighat, Siddiqi Mushtaq Ahmad, Muddassar Syed, Andrabi Khursheed Iqbal, Abdin Malik Zainul
Abstract excerpt
BACKGROUND AND AIM: The focus of the study was to investigate the frequencies of homozygous deletions and mutations of p16 gene in gastric carcinomas in the Kashmiri population. METHODS: A total of 84 gastric carcinoma patients were screened by the single strand conformation polymorphism (SSCP) technique and later by DNA sequencing to detect mutations of the p16 gene. Also PCR was applied further to further...
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