Can the microRNA signature distinguish between thyroid tumors of uncertain malignant potential and other well-differentiated tumors of the thyroid gland?

doi:10.1530/ERC-10-0283

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Article

Can the microRNA signature distinguish between thyroid tumors of uncertain malignant potential and other well-differentiated tumors of the thyroid gland?

Endocrine-related cancer - 1 Oct 2011

Lassalle Sandra, Hofman Véronique, Ilie Marius, Bonnetaud Christelle, Puisségur Marie-Pierre, Brest Patrick, Loubatier Céline, Guevara Nicolas, Bordone Olivier, Cardinaud Bruno, Lebrigand Kévin, Rios Géraldine, Santini Joseph, Franc Brigitte, Mari Bernard, Al Ghuzlan Abir, Vielh Philippe, Barbry Pascal, Hofman Paul

Abstract excerpt

The term 'thyroid tumors of uncertain malignant potential' (TT-UMP) was coined by surgical pathologists to define well-differentiated tumors (WDT) showing inconclusive morphological evidence of malignancy or benignity. We have analyzed the expression of microRNA (miRNA) in a training set of 42 WDT of different histological subtypes: seven follicular tumors of UMP (FT-UMP), six WDT-UMP, seven follicular thyroid...

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PMID: 21778212
DOI: 10.1530/ERC-10-0283

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