Article
A high prevalence of BRCA1 mutations among breast cancer patients from the Bahamas.
Breast cancer research and treatment - 1 Jan 2011
Donenberg Talia, Lunn John, Curling Duvaughn, Turnquest Theodore, Krill-Jackson Elisa, Royer Robert, Narod Steven A, Hurley Judith
Abstract excerpt
The Bahamas is a group of islands in the Caribbean with a high incidence of early onset breast cancer. In isolated populations, the identification of founder mutations in cancer predisposing genes may facilitate genetic testing and counseling. To date, six distinct BRCA1 mutations have been found in patients from cancer families from the Bahamas. The frequencies of these mutant alleles have not been measured in a...
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