Article
Longitudinal genome-wide association of cardiovascular disease risk factors in the Bogalusa heart study.
PLoS genetics - 9 Sept 2010
Smith Erin N, Chen Wei, Kähönen Mika, Kettunen Johannes, Lehtimäki Terho, Peltonen Leena, Raitakari Olli T, Salem Rany M, Schork Nicholas J, Shaw Marian, Srinivasan Sathanur R, Topol Eric J, Viikari Jorma S, Berenson Gerald S, Murray Sarah S
Abstract excerpt
Cardiovascular disease (CVD) is the leading cause of death worldwide. Recent genome-wide association (GWA) studies have pinpointed many loci associated with CVD risk factors in adults. It is unclear, however, if these loci predict trait levels at all ages, if they are associated with how a trait develops over time, or if they could be used to screen individuals who are pre-symptomatic to provide the opportunity...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.