Article
Cross resistance between oxytetracycline and oxolinic acid in Aeromonas salmonicida associated with alterations in outer membrane proteins.
FEMS microbiology letters - 1 Nov 1990
Barnes A C, Lewin C S, Hastings T S, Amyes S G
Abstract excerpt
Oxytetracycline resistant mutants of Aeromonas salmonicida isolated from mutation frequency experiments showed decreased susceptibility to oxolinic acid. Outer membrane preparations of these resistant mutant strains revealed a major protein, with a molecular mass of approximately 37 kDa, which was not present in significant quantities in the parent strain.
Topics
- Aeromonas
- Bacterial Outer Membrane Proteins
- Dose-Response Relationship, Drug
- Microbial Sensitivity Tests
- Mutation
- Oxolinic Acid
- Oxytetracycline
- Tetracycline Resistance