Article
A C1q-binding 40 kDa porin from Aeromonas salmonicida: cloning, sequencing, role in serum susceptibility and fish immunoprotection.
Microbial pathogenesis - 1 Jan 2000
Merino Susana, Vilches Silvia, Canals Rocío, Ramirez Silvia, Tomás Juan M
Abstract excerpt
A 40 kDa C1q-binding outer membrane protein from Aeromonas salmonicida was identified by direct-binding assay with biotinylated C1q, a subcomponent of the complement classical pathway component C1. The 40 kDa porin structural gene from the A450 A. salmonicida typical strain (A+:O+) was cloned in Escherichia coli and sequenced. The amino acid sequence of the 40 kDa A. salmonicida porin, its ability to bind C1q in...
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