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Article

Phospholipase C beta 1 deficiency is associated with early-onset epileptic encephalopathy.

Brain : a journal of neurology - 1 Oct 2010

Kurian Manju A, Meyer Esther, Vassallo Grace, Morgan Neil V, Prakash Nandhini, Pasha Shanaz, Hai Nebula A, Shuib Salwati, Rahman Fatima, Wassmer Evangeline, Cross J Helen, O'Callaghan Finbar J, Osborne John P, Scheffer Ingrid E, Gissen Paul, Maher Eamonn R

Abstract excerpt

The epileptic encephalopathies of infancy and childhood are a collection of epilepsy disorders characterized by refractory, severe seizures and poor neurological outcome, in which the mechanism of disease is poorly understood. We report the clinical presentation and evolution of epileptic encepha...

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Identifiers

PMID: 20833646
DOI: 10.1093/brain/awq238

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-20833646-2026-09-04.1. Manifest publication-graph-cohort-2026-09-04.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

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