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Increased integrity of circulating cell-free DNA in plasma of patients with acute leukemia

13 Sept 2010

Abstract excerpt

BACKGROUND: Increased cell-free DNA (cf-DNA) and the integrity of cf-DNA in plasma of patients with cancer has been described. We investigated the clinical utility of cf-DNA in the detection and monitoring of progression of leukemia. METHODS: Plasma samples from 60 patients with acute leukemia were analyzed in comparison to plasma from 30 healthy controls. Plasma DNA was determined by quantitative PCR (qPCR) by...

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PMID: 20831457
DOI: 10.1515/cclm.2010.311

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