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Article

A whole-genome SNP association study of NCI60 cell line panel indicates a role of Ca2+ signaling in selenium resistance.

PloS one - 7 Sept 2010

Savas Sevtap, Briollais Laurent, Ibrahim-zada Irada, Jarjanazi Hamdi, Choi Yun Hee, Musquera Mireia, Fleshner Neil, Venkateswaran Vasundara, Ozcelik Hilmi

Abstract excerpt

Epidemiological studies have suggested an association between selenium intake and protection from a variety of cancer. Considering this clinical importance of selenium, we aimed to identify the genes associated with resistance to selenium treatment. We have applied a previous methodology developed by our group, which is based on the genetic and pharmacological data publicly available for the NCI60 cancer cell...

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Source

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Identifiers

PMID: 20830292
DOI: 10.1371/journal.pone.0012601
PMCID: PMC2935366

Genes

AKAP6
KCNMA1
SGCD
PRKG1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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