Article
Polymorphisms of PXK are associated with autoantibody production, but not disease risk, of systemic lupus erythematosus in Chinese mainland population.
Lupus - 1 Jan 2011
Yu B, Wu Q, Chen Y, Li P, Shao Y, Zhang J, Zhong Q, Peng X, Yang H, Hu X, Chen B, Guan M, Zhang W, Wan J
Abstract excerpt
Systemic lupus erythematosus (SLE) is a complex immune disease. The genetic variation in the PXK gene was found to associate with SLE in Caucasian populations. However, the association of rs6445975 with SLE has not been extensively studied in a Chinese mainland population. A total of 288 SLE patients and 357 controls were recruited. Unlabeled probe-based high-resolution melting analysis (HRMA) was used in...
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