Article
Primary lesion radiotherapy during first-line icotinib treatment in EGFR-mutated NSCLC patients with multiple metastases and no brain metastases: a single-center retrospective study.
Strahlentherapie und Onkologie : Organ der Deutschen Rontgengesellschaft ... [et al] - 1 Dec 2022
Deng Rui, Liu Jinkun, Song Tongjun, Xu Tao, Li Yong, Duo Long, Xiang Longchao, Yu Xiongjie, Lei Jinhua, Cao Fengjun
Abstract excerpt
BACKGROUND: The most frequent mode of progression in the majority of non-small cell lung cancer (NSCLC) patients treated with Epidermal growth factor - receptor tyrosine kinase inhibitors (EGFR-TKIs) is failure to respond to treatment at the primary lesion, suggesting that concurrent radiotherapy (CRT) to the primary lesion (CPRT) during first-line treatment with EGFR-TKI may be a novel therapeutic approach with...
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