Gene-environment interactions in Parkinson's disease: the importance of animal modeling.

Abstract excerpt

Parkinson's disease (PD), a late-onset neurodegenerative disorder, occurs most commonly in a "sporadic" (idiopathic) form, without a clearly defined genetic basis and only a vaguely delineated pathogenesis. Together, the various monogenic forms of PD (i.e., those arising from mutations in single genes) account for a minority of PD cases but have provided crucial insights into disease mechanisms. Although it is...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Age Factors
• Share to Disease Models, Animal
• Share to Environment