Article
Microtubule actin crosslinking factor 1 regulates the Balbiani body and animal-vegetal polarity of the zebrafish oocyte.
PLoS genetics - 19 Aug 2010
Gupta Tripti, Marlow Florence L, Ferriola Deborah, Mackiewicz Katarzyna, Dapprich Johannes, Monos Dimitri, Mullins Mary C
Abstract excerpt
Although of fundamental importance in developmental biology, the genetic basis for the symmetry breaking events that polarize the vertebrate oocyte and egg are largely unknown. In vertebrates, the first morphological asymmetry in the oocyte is the Balbiani body, a highly conserved, transient structure found in vertebrates and invertebrates including Drosophila, Xenopus, human, and mouse. We report the...
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