Article
Changes in Mycobacterium tuberculosis genotype families over 20 years in a population-based study in Northern Malawi.
PloS one - 17 Aug 2010
Glynn Judith R, Alghamdi Saad, Mallard Kim, McNerney Ruth, Ndlovu Richard, Munthali Lumbani, Houben Rein M, Fine Paul E M, French Neil, Crampin Amelia C
Abstract excerpt
BACKGROUND: Despite increasing interest in possible differences in virulence and transmissibility between different genotypes of M. tuberculosis, very little is known about how genotypes within a population change over decades, or about relationships to HIV infection. METHODS AND PRINCIPAL FINDINGS: In a population-based study in rural Malawi we have examined smears and cultures from tuberculosis patients over a...
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