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Article

A Mycobacterial Perspective on Tuberculosis in West Africa: Significant Geographical Variation of M. africanum and Other M. tuberculosis Complex Lineages.

PLoS neglected tropical diseases - 1 Mar 2016

Gehre Florian, Kumar Samrat, Kendall Lindsay, Ejo Mebrat, Secka Oumie, Ofori-Anyinam Boatema, Abatih Emmanuel, Antonio Martin, Berkvens Dirk, de Jong Bouke C

Abstract excerpt

BACKGROUND: Phylogenetically distinct Mycobacterium tuberculosis lineages differ in their phenotypes and pathogenicity. Consequently, understanding mycobacterial population structures phylogeographically is essential for design, interpretation and generalizability of clinical trials. Comprehensive efforts are lacking to date to establish the West African mycobacterial population structure on a sub-continental...

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Identifiers

PMID: 26964059
DOI: 10.1371/journal.pntd.0004408
PMCID: PMC4786107

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