Article
Does large scale DNA sequencing of patient and tumor DNA yet provide clinically actionable information?
Discovery medicine - 1 Aug 2010
Harris Tim
Abstract excerpt
There have been several publications recently that reported DNA sequence alterations in human tumors. There are gene deletions, amplifications, point mutations, translocations, and other genome changes in these samples compared to normal controls. There is also considerable variation in the number of such changes seen in different cancers. Some of the changes particularly those that are mutations in genes driving...
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