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Article

Development of a high resolution melting method for the detection of genetic variations in hypertrophic cardiomyopathy.

Clinica chimica acta; international journal of clinical chemistry - 14 Dec 2010

Millat Gilles, Chanavat Valérie, Créhalet Hervé, Rousson Robert

Abstract excerpt

BACKGROUND: Hypertrophic cardiomyopathy (HCM) is the most common genetic cardiac disease affecting 1 in 500 people. Due to large cohorts to investigate, the number of disease-causing genes, the size of the 2 prevalent mutated genes, and the presence of a large spectrum of private mutations, mutational screening must be performed using an extremely sensitive and specific scanning method. METHODS: High Resolution...

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Share to Cardiomyopathy, Hypertrophic
Share to Chromatography, High Pressure Liquid

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to TNNI3 gene

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Share to Nucleic Acid Denaturation

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Source

Identifiers

PMID: 20800588
DOI: 10.1016/j.cca.2010.08.017

Genes

MYBPC3
MYH7
TNNI3
TNNT2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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