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Article

Rapid, sensitive and inexpensive detection of SCN5A genetic variations by high resolution melting analysis.

Clinical biochemistry - 1 Apr 2009

Millat Gilles, Chanavat Valérie, Rodriguez-Lafrasse Claire, Rousson Robert

Abstract excerpt

OBJECTIVES: SCN5A mutations lead to a wide spectrum of cardiovascular disorders. Due to large cohorts to investigate and the large gene size, mutational screening must be performed using an extremely sensitive and specific scanning method. DESIGN AND METHODS: High Resolution Melting (HRM) analysis was developed for SCN5A mutation detection using control DNAs and DNAs carrying previously identified gene variants....

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Identifiers

PMID: 19026623
DOI: 10.1016/j.clinbiochem.2008.10.014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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