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Article

Role of microRNA-199a-5p and discoidin domain receptor 1 in human hepatocellular carcinoma invasion

27 Aug 2010

Abstract excerpt

BACKGROUND: Micro-ribonucleic acid (miRNA)-199a-5p has been reported to be decreased in hepatocellular carcinoma (HCC) compared to normal tissue. Discoidin domain receptor-1 (DDR1) tyrosine kinase, involved in cell invasion-related signaling pathway, was predicted to be a potential target of miR-199a-5p by the use of miRNA target prediction algorithms. The aim of this study was to investigate the role of...

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PMID: 20799954
DOI: 10.1186/1476-4598-9-227

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