Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Transcriptional activation of the IGF-II/IGF-1R axis and inhibition of IGFBP-3 by miR-155 in hepatocellular carcinoma

18 Sept 2015

Abstract excerpt

Hepatocellular carcinoma (HCC) is characterized by the aberrant expression of a number of genes that govern crucial signaling pathways. The insulin-like growth factor (IGF) axis is important in this context, and the precise regulation of expression of members of this axis is known to be lost in HCC. miR-155 is a well-established oncogene in numerous types of cancer. However, to the best of our knowledge, its...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Cancer, Hypoxia, and Metabolism
Share to Growth Hormone and Insulin-like Growth Factors
Share to Liver Disease Diagnosis and Treatment

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Source

Identifiers

PMID: 26722313
DOI: 10.3892/ol.2015.3725

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Transcriptional activation of the IGF-II/IGF-1R axis and inhibition of IGFBP-3 by miR-155 in hepatocellular carcinomaPMID 26722313Read ↗

MiR-155 and its functional variant rs767649 contribute to the susceptibility and survival of hepatocellular carcinoma.Semantic proximity Read ↗

Up-Regulation of MicroRNA-190b Plays a Role for Decreased IGF-1 That Induces Insulin Resistance in Human Hepatocellular CarcinomaSemantic proximity Read ↗

Insulin-like Growth Factor I Receptor: A Novel Target for Hepatocellular Carcinoma Gene TherapySemantic proximity Read ↗

miR155 Enhances Autophagy by Reducing MBD5 and METTL3 in Human Liver Cancer Stem CellsSemantic proximity Read ↗

MiR-205-3p Modulates Hepatocellular Carcinoma-Derived Endothelial Cell Progression through suppression of HINT1Semantic proximity Read ↗

MicroRNA-195 suppresses tumorigenicity and regulates G1/S transition of human hepatocellular carcinoma cells #Semantic proximity Read ↗

MiR-455-3p inhibits hepatocellular carcinoma tumorigenesis, lymphangiogenesis and angiogenesis via regulating vascular endothelial growth factor C and vascular endothelial growth factor receptor-2Semantic proximity Read ↗

miR-195 inhibits cell proliferation via targeting AEG-1 in hepatocellular carcinomaSemantic proximity Read ↗

Ectopic expression of microRNA-155 enhances innate antiviral immunity against HBV infection in human hepatoma cellsSemantic proximity Read ↗

miR‑197 promotes the invasion and migration of colorectal cancer by targeting insulin‑like growth factor‑binding protein 3.Semantic proximity Read ↗

Interaction analysis of miR-1275/IGF2BP1/IGF2BP3 with the susceptibility to hepatocellular carcinoma.Semantic proximity Read ↗

Blocking lncRNA MIR155HG/miR-155-5p/-3p inhibits proliferation, invasion and migration of clear cell renal cell carcinomaSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.