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Article

MicroRNA-205 promotes cell invasion by repressing TCF21 in human ovarian cancer

5 May 2017

Abstract excerpt

BACKGROUND: Ovarian cancer is the leading lethal, gynecological malignancy in the United States. No doubt, the continued morbidity and mortality of ovarian cancer reflects a poor understanding of invasive mechanisms. Recent studies reveal that ovarian cancers express aberrant microRNAs (miRNAs or miRs), some of which have oncogenic or tumor suppressor properties. Several studies suggested that miR-205 is involved...

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PMID: 28476165
DOI: 10.1186/s13048-017-0328-1

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