Article
Genomic acquisition of a capsular polysaccharide virulence cluster by non-pathogenic Burkholderia isolates.
Genome biology - 1 Jan 2010
Sim Bernice Meng Qi, Chantratita Narisara, Ooi Wen Fong, Nandi Tannistha, Tewhey Ryan, Wuthiekanun Vanaporn, Thaipadungpanit Janjira, Tumapa Sarinna, Ariyaratne Pramila, Sung Wing-Kin, Sem Xiao Hui, Chua Hui Hoon, Ramnarayanan Kalpana, Lin Chi Ho, Liu Yichun, Feil Edward J, Glass Mindy B, Tan Gladys, Peacock Sharon J, Tan Patrick
Abstract excerpt
BACKGROUND: Burkholderia thailandensis is a non-pathogenic environmental saprophyte closely related to Burkholderia pseudomallei, the causative agent of the often fatal animal and human disease melioidosis. To study B. thailandensis genomic variation, we profiled 50 isolates using a pan-genome microarray comprising genomic elements from 28 Burkholderia strains and species. RESULTS: Of 39 genomic regions variably...
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