Article
Twin studies and their implications for molecular genetic studies: endophenotypes integrate quantitative and molecular genetics in ADHD research.
Journal of the American Academy of Child and Adolescent Psychiatry - 1 Sept 2010
Wood Alexis C, Neale Michael C
Abstract excerpt
OBJECTIVE: To describe the utility of twin studies for attention-deficit/hyperactivity disorder (ADHD) research and demonstrate their potential for the identification of alternative phenotypes suitable for genomewide association, developmental risk assessment, treatment response, and intervention targets. METHOD: Brief descriptions of the classic twin study and genetic association study methods are provided, with...
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