Article
Nuclear factor I-C regulates TGF-{beta}-dependent hair follicle cycling.
The Journal of biological chemistry - 29 Oct 2010
Plasari Genta, Edelmann Simone, Högger Florence, Dusserre Yves, Mermod Nicolas, Calabrese Alessandra
Abstract excerpt
Skin appendages such as teeth and hair share several common signaling pathways. The nuclear factor I C (NFI-C) transcription factor has been implicated in tooth development, but a potential role in hair growth had not been assessed. In this study we found that NFI-C regulates the onset of the hair growth cycle. NFI-C(-/-) mice were delayed in the transition from the telogen to anagen phase of the hair follicle...
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