Article
Major histocompatibility complex variation and age-specific endoparasite load in subadult European rabbits.
Molecular ecology - 1 Oct 2010
Oppelt Claus, Starkloff Anett, Rausch Philipp, Von Holst Dietrich, Rödel Heiko G
Abstract excerpt
Genes of the major histocompatibility complex (MHC) play a fundamental role in the vertebrate immune response and are amongst the most polymorphic genes in vertebrate genomes. It is generally agreed that the highly polymorphic nature of the MHC is maintained through host-parasite co-evolution. Two nonexclusive mechanisms of selection are supposed to act on MHC genes: superiority of MHC heterozygous individuals...
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