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Article

Phenotypic and genetic analysis of the cerebellar mutant tmgc26, a new ENU-induced ROR-alpha allele.

The European journal of neuroscience - 1 Sept 2010

Swanson Douglas J, Steshina Ekaterina Y, Wakenight Paul, Aldinger Kimberly A, Goldowitz Dan, Millen Kathleen J, Chizhikov Victor V

Abstract excerpt

ROR-alpha is an orphan nuclear receptor, inactivation of which cell-autonomously blocks differentiation of cerebellar Purkinje cells with a secondary loss of granule neurons. As part of our ENU mutagenesis screen we isolated the recessive tmgc26 mouse mutant, characterized by early-onset progress...

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Identifiers

PMID: 20722722
DOI: 10.1111/j.1460-9568.2010.07330.x
PMCID: PMC2974799

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20722722-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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