Article
Microarray-based comparative genomic hybridization (array-CGH) as a useful tool for identifying genes involved in Glioblastoma (GB).
Methods in molecular biology (Clifton, N.J.) - 1 Jan 2010
Ruano Yolanda, Mollejo Manuela, de Lope Angel Rodríguez, Hernández-Moneo José Luis, Martínez Pedro, Meléndez Bárbara
Abstract excerpt
Alterations in the genome that lead to changes in DNA sequence copy number are a characteristic of Glioblastomas (GBs). Microarray-based comparative genomic hybridization (array-CGH) is a high-throughput technology that allows the hybridization of genomic DNA onto conventional cDNA microarrays, normally used in expression profiling, to analyze genomic copy number imbalances. In this way, thousands of genes can be...
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