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Article

Systematic assessment of protein phenotypes characterizing high-grade tumour budding in mismatch repair-proficient colorectal cancer.

Histopathology - 1 Aug 2010

Karamitopoulou Eva, Lugli Alessandro, Panayiotides Ioannis, Karakitsos Petros, Peros George, Rallis George, Patsouris Efstratios S, Terracciano Luigi, Zlobec Inti

Abstract excerpt

AIMS: A tumour bud is defined as a single tumour cell or tumour cell cluster of up to five cells at the invasive tumour front. Significant differences in survival have been detected in colorectal cancer patients with low- compared to high-grade budding. The aim of this study was to identify potential multi-marker phenotypes characterizing low- and high-grade budding in mismatch repair (MMR)-proficient colorectal...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 20716165
DOI: 10.1111/j.1365-2559.2010.03615.x

Genes

CDX2
EGFR
MST1
MUC1

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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