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ABCG5-positivity in tumor buds is an indicator of poor prognosis in node-negative colorectal cancer patients

1 Jan 2010

Abstract excerpt

AIM: To analyze the expression of 8 putative cancer stem cell (CSC) markers within colorectal cancer tumor buds and to determine their prognostic impact in patients with this disease. METHODS: Immunohistochemistry was performed on 101 colorectal cancer resections for CK22 (to identify tumor buds) as well as CD133, CD166, CD24, CD44s, CD90, EpCAM, ALDH1, and ABCG5, and their expression within tumor buds was...

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PMID: 20135722
DOI: 10.3748/wjg.v16.i6.732

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