Article
Ingenuity pathways analysis of urine metabolomics phenotypes toxicity of Chuanwu in Wistar rats by UPLC-Q-TOF-HDMS coupled with pattern recognition methods.
Molecular bioSystems - 1 Apr 2012
Dong Hui, Zhang Aihua, Sun Hui, Wang Huiyu, Lu Xin, Wang Mo, Ni Bei, Wang Xijun
Abstract excerpt
Chuanwu (CW), a valuable traditional Chinese medicine (TCM), is the mother root of Aconitum carmichaelii Debx. The cause of CW-induced toxicity is still under ongoing research, although this is limited by the lack of sensitive and reliable biomarkers. Ingenuity pathway analysis (IPA) was performed to analyzing global metabolomics in order to characterize the phenotypically biochemical perturbations and potential...
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