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Article

Relationship of BRCA1 and BRCA2 mutations with cancer burden in the family and tumor incidence.

Familial cancer - 1 Sept 2010

Esteban Cardeñosa Eva, Bolufer Gilabert Pascual, de Juan Jiménez Inmaculada, Palanca Suela Sarai, Barragán González Eva, González Anguix Virginia, Lerma Alejos Enrique, Chirivella González Isabel, Segura Huerta Angel, Guillén Ponce Carmen, Martínez de Dueñas Eduardo, Cuevas Cuerda Dolores, Salas Trejo Dolores

Abstract excerpt

The aim of the present study is to analyze the relationship of the incidence of mutations in the two major genes BRCA1 and BRCA2 conferring risk of breast cancer (BC) and ovarian cancer (OC) with the cancer burden in families and with the presence and age of onset of BC/OC. We included 704 index...

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Source

Identifiers

PMID: 20711702
DOI: 10.1007/s10689-010-9327-8

Genes

BRCA1
BRCA2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20711702-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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