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Article

Stimulating effect of external Myo-inositol on the expression of mutant forms of aquaporin 2.

The Journal of membrane biology - 1 Jul 2010

Lussier Yoann, Bissonnette Pierre, Bichet Daniel G, Lapointe Jean-Yves

Abstract excerpt

Myo-inositol (MI; hexahydroxycyclohexane, C(6)H(6)O(12)) is a small neutral molecule used as a compatible osmolyte in the kidney medulla. At high concentrations, MI appears to act as a chemical chaperone and was shown to promote plasma membrane expression of the impaired cystic fibrosis chloride...

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Source

Identifiers

PMID: 20711567
DOI: 10.1007/s00232-010-9295-9

Genes

AQP2
CFTR

Variants

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20711567-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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