Article
Does myo-inositol effect on PCOS follicles involve cytoskeleton regulation?
Medical hypotheses - 1 Jun 2016
Bizzarri Mariano, Cucina Alessandra, Dinicola Simona, Harrath Abdel Halim, Alwasel Saleh H, Unfer Vittorio, Bevilacqua Arturo
Abstract excerpt
Inositol metabolism is severely impaired in follicles obtained from cystic ovaries, leading to deregulated insulin transduction and steroid synthesis. On the contrary, inositol administration to women suffering from polycystic ovary syndrome (PCOS) has been proven to efficiently counteract most of the clinical hallmarks displayed by PCOS patients, including insulin resistance, hyperandrogenism and...
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