Expression of hsp90 mediates cytoprotective effects in the gastrodermis of planarians.

doi:10.1007/s12192-010-0218-6

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Article

Expression of hsp90 mediates cytoprotective effects in the gastrodermis of planarians.

Cell stress & chaperones - 1 Jan 2011

Conte Maria, Isolani Maria Emilia, Deri Paolo, Mannini Linda, Batistoni Renata

Abstract excerpt

Heat shock proteins (HSPs) play a crucial role in the protection of cells. In the present study, we have identified an hsp90-related gene (Djhsp90) encoding a cytosolic form of HSP90 that is primarily expressed in gastrodermis of the planarian Dugesia japonica. Djhsp90 becomes significantly induced after traumatic amputation or other stress stimuli, such as exposure to X-ray or ultraviolet radiations, heat shock,...

Topics

Animals
Cytoprotection
HSP90 Heat-Shock Proteins
Intestinal Mucosa
Phenotype
Planarians
RNA Interference
Temperature
Ultraviolet Rays
X-Rays

Source

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Identifiers

PMID: 20706815
DOI: 10.1007/s12192-010-0218-6
PMCID: PMC3024083

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