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Article

RET-Mediated Cell Adhesion and Migration Require Multiple Integrin Subunits

12 Aug 2010

Abstract excerpt

CONTEXT: The RET receptor tyrosine kinase is an important mediator of several human diseases, most notably of neuroendocrine cancers. These diseases are characterized by aberrant cell migration, a process tightly regulated by integrins. OBJECTIVE: Our goals were to investigate the role of integrins in RET-mediated migration in two neoplastic cell models: the neural-derived cell line SH-SY5Y, and the papillary...

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PMID: 20702524
DOI: 10.1210/jc.2010-0771

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