Article
Genome-wide association studies of serum magnesium, potassium, and sodium concentrations identify six Loci influencing serum magnesium levels.
PLoS genetics - 5 Aug 2010
Meyer Tamra E, Verwoert Germaine C, Hwang Shih-Jen, Glazer Nicole L, Smith Albert V, van Rooij Frank J A, Ehret Georg B, Boerwinkle Eric, Felix Janine F, Leak Tennille S, Harris Tamara B, Yang Qiong, Dehghan Abbas, Aspelund Thor, Katz Ronit, Homuth Georg, Kocher Thomas, Rettig Rainer, Ried Janina S, Gieger Christian, Prucha Hanna, Pfeufer Arne, Meitinger Thomas, Coresh Josef, Hofman Albert, Sarnak Mark J, Chen Yii-Der Ida, Uitterlinden André G, Chakravarti Aravinda, Psaty Bruce M, van Duijn Cornelia M, Kao W H Linda, Witteman Jacqueline C M, Gudnason Vilmundur, Siscovick David S, Fox Caroline S, Köttgen Anna
Abstract excerpt
Magnesium, potassium, and sodium, cations commonly measured in serum, are involved in many physiological processes including energy metabolism, nerve and muscle function, signal transduction, and fluid and blood pressure regulation. To evaluate the contribution of common genetic variation to normal physiologic variation in serum concentrations of these cations, we conducted genome-wide association studies of...
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