Article
Epidermal and dermal integration into sphere-templated porous poly(2-hydroxyethyl methacrylate) implants in mice.
Journal of biomedical materials research. Part A - 15 Sept 2010
Fukano Y, Usui M L, Underwood R A, Isenhath S, Marshall A J, Hauch K D, Ratner B D, Olerud J E, Fleckman P
Abstract excerpt
Percutaneous medical devices remain susceptible to infection and failure. We hypothesize that healing of the skin into the percutaneous device will provide a seal, preventing bacterial attachment, biofilm formation, and subsequent device failure. Porous poly(2-hydroxyethyl methacrylate) [poly(HEMA)] with sphere-templated pores (40 microm) and interconnecting throats (16 microm) were implanted in normal C57BL/6...
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