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Article

Characterization of substrate preference for Slc1p and Cst26p in Saccharomyces cerevisiae using lipidomic approaches and an LPAAT activity assay.

PloS one - 4 Aug 2010

Shui Guanghou, Guan Xue Li, Gopalakrishnan Pradeep, Xue Yangkui, Goh Joyce Sze Yuin, Yang Hongyuan, Wenk Markus R

Abstract excerpt

BACKGROUND: Phosphatidic acid (PA) is a key regulated intermediate and precursor for de novo biosynthesis of all glycerophospholipids. PA can be synthesized through the acylation of lysophosphatidic acid (LPA) by 1-acyl-3-phosphate acyltransferase (also called lysophosphatidic acid acyltransferase, LPAAT). Recent findings have substantiated the essential roles of acyltransferases in various biological functions....

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Identifiers

PMID: 20694142
DOI: 10.1371/journal.pone.0011956
PMCID: PMC2915916

Genes

LPA

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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