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Article

CellCognition: time-resolved phenotype annotation in high-throughput live cell imaging.

Nature methods - 1 Sept 2010

Held Michael, Schmitz Michael H A, Fischer Bernd, Walter Thomas, Neumann Beate, Olma Michael H, Peter Matthias, Ellenberg Jan, Gerlich Daniel W

Abstract excerpt

Fluorescence time-lapse imaging has become a powerful tool to investigate complex dynamic processes such as cell division or intracellular trafficking. Automated microscopes generate time-resolved imaging data at high throughput, yet tools for quantification of large-scale movie data are largely missing. Here we present CellCognition, a computational framework to annotate complex cellular dynamics. We developed a...

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Identifiers

PMID: 20693996
DOI: 10.1038/nmeth.1486

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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