Article
Cardiac hypertrophy, low blood pressure, and low aldosterone levels in mice devoid of the three circadian PAR bZip transcription factors DBP, HLF, and TEF.
American journal of physiology. Regulatory, integrative and comparative physiology - 1 Oct 2010
Wang Qing, Maillard Marc, Schibler Ueli, Burnier Michel, Gachon Frédéric
Abstract excerpt
The cardiovascular system is under the control of the circadian clock, and disturbed circadian rhythms can induce cardiovascular pathologies. This cyclic regulation is probably brought about by the circadian expression of genes encoding enzymes and regulators involved in cardiovascular functions....
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