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Article

Nanoconjugation modulates the trafficking and mechanism of antibody induced receptor endocytosis.

Proceedings of the National Academy of Sciences of the United States of America - 17 Aug 2010

Bhattacharyya Sanjib, Bhattacharya Resham, Curley Steven, McNiven Mark A, Mukherjee Priyabrata

Abstract excerpt

Treatment with monoclonal antibody (mAbs) is a viable therapeutic option in cancer. Recently, these mAbs such as cetuximab, herceptin, etc., have been used as targeting agents to selectively deliver chemotherapeutics to cancerous cells. However, mechanisms of nanoparticles-mAbs interactions with...

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Identifiers

PMID: 20679244
DOI: 10.1073/pnas.1006507107
PMCID: PMC2930461

Genes

EGFR

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 2 Sept 2026. Prepared record publication-20679244-2026-09-02.2. Manifest publication-graph-cohort-2026-09-02.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 2 Sept 2026.

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