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Article

Different functions of the C3HC4 zinc RING finger peroxins PEX10, PEX2, and PEX12 in peroxisome formation and matrix protein import.

Proceedings of the National Academy of Sciences of the United States of America - 17 Aug 2010

Prestele Jakob, Hierl Georg, Scherling Christian, Hetkamp Stefan, Schwechheimer Claus, Isono Erika, Weckwerth Wolfram, Wanner Gerhard, Gietl Christine

Abstract excerpt

The integral peroxisomal membrane proteins PEX10, PEX2, and PEX12 contain a zinc RING finger close to the C terminus. Loss of function of these peroxins causes embryo lethality at the heart stage in Arabidopsis. Preventing the coordination of Zn(2+) ions by amino acid substitutions in PEX10, PEX2, and PEX12 and overexpressing the resulting conditional sublethal mutations in WT uncovered additional functions of...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 20679226
DOI: 10.1073/pnas.1009174107
PMCID: PMC2930433

Genes

PEX10
PEX12
PEX2
PEX5

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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Different functions of the C3HC4 zinc RING finger peroxins PEX10, PEX2, and PEX12 in peroxisome formation and matrix protein import.PMID 20679226Read ↗

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